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B Vitamins

The Cognitive Related Role Of B Vitamins Within The Body

B vitamins are very important for our brains. It plays an important role in the body as a nootropic substance and helps to enhance our brain functions. Vitamin B can significantly lower the levels of serum Hcy and prevent the decline of global cognitive functions. Vitamins play a key role in ensuring the health of the brain in children and adults. In this article, we will explain the cognitive related role of B vitamins within the body.

The deficiency of B vitamins can slow down brain functions and result in delayed development. However, the results can even worsen, such as low learning capabilities or lessened thinking ability, low alternates, etc. So read the article, till the end to know the importance of vitamin B, its causes, symptoms of vitamin B deficiency, and more.

The Cognitive Related Role Of B Vitamins

The Cognitive Related Role Of B Vitamins

Lack of Vitamin B’s and absorption can lead to certain neurodegenerative diseases. Therefore, B vitamins are essential for our body and the brain too. They are essential in processes ranging from glucose energy metabolism to the production of neurotransmitters such as acetylcholine and monoamine.

The structure of B vitamins can also be duplicated as choline in several nootropic drugs. In this article, we want you to know the importance of each B vitamin and how they work. Alongside, we will also tell you about possible medications that may be beneficial for you. However, remember that supplementation will only work if your body lacks these vitamins.

An excessive dosage of B vitamins is harmful and toxic. Our body cannot synthesize some vitamins, therefore we need to take them from foods, and supplements. Most people get different types of vitamin B through their diets.

Symptoms of Vitamin B Deficiency

Some common symptoms of vitamin B deficiency are mentioned below.

  • Fatigue
  • Insomnia
  • Low levels of energy
  • The problem of recalling due to low acetylcholine synthesis.
  • Nausea
  • Indigestion
  • Low moodiness, forgetfulness, and alertness.

Important B Vitamins for Cognition

There are only eight types of vitamin B. Vitamin B is vital for brain health and overall health. B vitamins are water-soluble, and they cannot be stored in the body. Therefore, our body needs an adequate amount of B vitamins from different sources such as supplements, food, plant-based products, meat, dairy products, etc.

Vitamin B1 or Thiamine

Vitamin B is also known as thiamine. It is a B vitamin that is required for life. This vitamin is involved in various functions in the body. Thiamine plays an important role in nerve function as well. Vitamin B1 is used in acetylcholine and biosynthesis. Poor coordination, confusion, fatigue, memory problems, and anger can happen if you don’t get enough vitamin B1.

Vitamin B1 can be found in cereals, grains, nuts, yeast, flax, pork, and seeds. Generally, vitamin B deficiency is found in those countries where rice is a dietary staple.

Sulbutiamine – B1 Derivative

Sulbutiamine is a derivative of vitamin B1. It can be absorbed by the blood-brain barrier easily. It has noticeable nootropic effects on cognition, such as increased memory, improved learning, and high energy levels.

Vitamin B5 or Pantothenic Acid

Vitamin B5, or Pantothenic acid, is another vital B vitamin for cognitive functions. Well, this vitamin is not a popular form of B vitamin, but it plays a crucial role in brain functions. You can obtain vitamin B5 from the similar foods that are mentioned for vitamin B1. You can find enough vitamin 5 in grains.

Vitamin B5 is useful in converting coenzyme A to form acetyl-CoA. When Acetyl-CoA and Choline are joined, they form Acetylcholine. Without acetyl-CoA, choline cannot be synthesized into acetylcholine. Hence, vitamin B5 is necessary to form acetylcholine, which is important for the brain.

Vitamin B6 or Pyridoxine 

Vitamin B6 is a very important type of B vitamin. It is beneficial for cognitive function, as well as mental well-being and good mood. This vitamin has no connection with acetylcholine, but it influences monoamine transmitters such as dopamine, serotonin, epinephrine, and norepinephrine.

Vitamin b6 is an important intermediator in synthesizing monoamines. The deficiency of vitamin B6 is rare. The majority of people get it through their diets and other sources. However, a lack of vitamin B6 in our bodies can have a negative impact on cognitive functions and mood.


Pyritinol is a nootropic supplement for vitamin B6. It is used as an over-the-counter nootropic supplement in many countries. Scientists and not sure about how pyritinol works. It affects acetylcholine and reuptake.  A higher level of ATP and glucose is the main benefit of pyritinol.

Vitamin B12 Or Cobalamin

Vitamin B12 is one of the important B vitamins for nootropic effects in the body. It is one of the most complex of all the B vitamins. It plays an essential role in a variety of biological functions. Due to the complexity of vitamin B12, it is broken down into different vitamers. Cyanocobalamin is a substitute for vitamin B12 and is often used in place of cobalamin.

Vitamin 12 is known for its perpetuated effects on the brain atrophy linked with Alzheimer’s. Vitamin B12 deficiency can lead to declining cognition associated with Alzheimer’s. Vitamin B12 has highly neuroprotective effects on the brain.


Technically, choline is not a vitamin B complex, but structurally, it can be treated as a B vitamin. It is a water-soluble nutrient that can be obtained from different diets. Several types of B vitamins include choline in their structure. Choline deficiency is very common. A group of people who are vegan, or post-menopausal women, athletes, and the elderly can experience choline deficiency.

Bottom Line

In a nutshell, B vitamins can lower serum Hcy levels, and improve overall cognitive functions. As per the researchers, vitamin B supplements can help to delay or manage the cognitive decline in elderly people. Cognitive impairment can be prevented by taking B-complex vitamin supplements. However, ask your doctor before taking any medicine or supplements.

The cognitive-related role of B vitamins within the body is complex. It helps to scale up cognitive functions. The optimal dosage of b vitamins can enhance your brain only if your body lacks them, otherwise not.

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