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A Primer On Sulbutiamine – How to Use Sulbutiamine?

Sulbutiamine is a precursor to thiamine. It is one of the main nootropics in the group of over-the-counter nootropics. It is a human-created chemical that acts similarly to Vitamin B or thiamine, but it can cross the blood-brain barrier much more easily and increase thiamine levels. In this article, we will provide a primer on sulbutiamine.

We have focused on the medical features and uses, side effects, benefits, recommended dosage, and how to use sulbutiamine. This article will provide you with detailed information on sulbutiamine. So, let’s get started.

A Primer on Sulbutiamine – What It Is?

A Primer on Sulbutiamine

Sulbutiamine falls under the category of nootropics. Nootropics, or smart drugs, are available as over-the-counter supplements to increase and enhance cognitive abilities. Sulbutiamine is one common type of nootropic supplement that barely needs a prescription. Sulbutiamine acts similar to Vitamin B1 or thiamine.

Unlike vitamin B1, sulbutiamine is also a fat-soluble chemical. It can dissolve in fat. Sulbutiamine is used in a variety of nootropics. It can easily cross the blood-brain barrier, and the body metabolizes it as thiamine. After that, the brain will use them to produce neurotransmitters like acetylcholine and GABA.

Additionally, it also has glutamatergic transmissions. Glutamate is the main neurotransmitter that is responsible for excitement. It plays an important role in learning and memory functions.

Sulbutiamine is taken orally for weakness, athletic performance, depression, Alzheimer’s, diabetes, nerve damage, fatigue, erectile dysfunction, and memory functions. It also helps to reduce dopamine, and the D1 dopamine receptors boost the overall mood.

Sulbutiamine Features

Sulbutiamine was initially developed for the treatment of beriberi. This condition leads to feelings of fatigue and lethargy. However, sulbutiamine is currently used as a treatment for several health conditions.

Some studies show that sulbutiamine is an effective nootropic supplement for psychogenic erectile dysfunction. It means that men who are suffering from erectile dysfunction due to some issues like depression, stress, and anxiety can overcome their problems and get relief.

However, you might be thinking that it’s not a big deal because there are various treatments available, but sulbutiamine is a cheaper and safer option available on the market.

Sulbutiamine is also used for the treatment of asthenia. In asthenia conditions, people feel fatigued. Furthermore, due to its nootropic qualities and memory-improving qualities, sulbutiamine is also used by patients suffering from schizophrenia and Alzheimer’s disease.


The major benefits of sulbutiamine are mentioned below.

  • increase memory levels.
  • improved memory.
  • better focus.
  • enhance the overall mood.

How to Use Sulbutiamine

Sulbutiamine is a type of nootropic drug that you don’t need to take daily. Although it is safe and will not be dangerous if you consume it daily, But your brain becomes used to it and it builds tolerance, which will lead to losing the effectiveness of this drug.

Therefore, it is best to take Sulbutiamine on alternate days to maintain the effectiveness of this nootropic. Sulbutiamine is a quite effective and safer alternative to the nootropics or drugs marketed with less subtle effects.

Sulbutiamine is available in capsule and bulk powder form. The powder form is cost-effective but foul in taste. If you want to use the powder form of sulbutiamine, dissolve it in water and consume it. However, you can also opt for capsules by purchasing your capping machine and creating your own sulbutiamine capsules.

Side Effects

No supplement comes without side effects, even the safer supplements also have certain negative effects. Although this nootropic is published as a safe nootropic supplement, it is safer than the stimulant supplements currently available on the market.

Remember that this supplement does not cause side effects if you take the recommended dosage. At a standard dosage of 850mg per day, you may experience only skin allergies. No major side effects or serious health issues have been reported yet.

Recommended Dosage

The recommended dosage of sulbutiamine is 850 mg per day, for a person weighing 150 pounds. Well, if your weight is higher than 150 pounds, you need to increase the dosage and visa-versa.

Some studies show that you should not use more than 600mg of sulbutiamine, but even at 850mg per day, only mild skin allergies appear. For your safety, don’t exceed the dose of 600mg per day until you are using it for some specific condition.

Also, make sure to take sulbutiamine once per day. Don’t double the dose or divide the entire dose into small pieces. The effects of sulbutiamine will last for five hours, after which the effect starts diminishing.

The appropriate dosing of sulbutiamine depends on various factors such as health, age, condition, and other factors. There isn’t enough evidence right now to say how much sulbutiamine should be taken to get the best results.

Special Warnings

There is less reliable information available regarding sulbutiamine for pregnant or breastfeeding women. For safety reasons, avoid using sulbutiamine, if you are breastfeeding or pregnant. Moreover, people going through psychiatric disorders may not be likely to abuse this drug. Due to less information, people with psychiatric conditions should use sulbutiamine carefully.

Sulbutiamine Effectiveness

The effectiveness of sulbutiamine can be tested by the points listed below.

Sulbutiamine can be effective for fatigue. In one study, it was found that daily consumption of sulbutiamine for 28 days can reduce fatigue and weakness.

Sulbutiamine is also powerful in early-stage Alzheimer’s disease. Taking this drug for four weeks can improve attention and focus.

Research suggests that sulbutiamine can also reduce an aspect of depression called psycho-behavioral inhibition.

It can improve erectile dysfunction, diabetes, nerve damage, pain, sharpen memory, performance, and more.


Sulbutiamine is an awesome nootropic drug that can boost mental ability. It is an excellent option for all those who want to boost their brainpower. In our blog, a primer on sulbutiamine, you have seen the effectiveness of this drug. Moreover, it is safer than the stimulant alternatives marketed.

They may cause side effects, but sulbutiamine is a safer version, and it is free from moderate side effects. Hence, sulbutiamine could be effective and safe for use.

Also Read:

The Cognitive Related Role of B Vitamins
Mushroom Nootropic Supplement Review

Matthew Swayne

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