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Acetyl L-Carnitine

Does Acetyl L-Carnitine Work as a Nootropic?

Does Acetyl L-Carnitine Work as a Nootropic?: Many dairy and meat products help us synthesize L-carnitine, but what is L-carnitine? In actuality, L-carnitine is both a nutrient and an energy provider for our body. It is a conditional nutrient that helps in providing energy for our mitochondria.

But Acetyl L-carnitine is very different from L-carnitine, so we have to explore how Acetyl L-carnitine works as a nootropic.

Here we will be talking about the supplemental form of Acetyl L-Carnitine and the biochemistry involved within our body, and its effect on our brain health.

Does Acetyl L-Carnitine Work as a Nootropic?

Does Acetyl L-Carnitine Work as a Nootropic?

What is Acetyl L-Carnitine?

Acetyl L-carnitine is a synthesized L-carnitine, a type of amino acid that is naturally produced inside the human body and is better known as L-Carnitine or ALCAR.

It first breaks down in the form of carnitine, which can simply be understood as a substance found in muscle and liver tissue to exert energy from the long chain of fatty acids.

This component helps the body to break down the transported fatty acids through the mitochondria, but apart from acting as a potential nutrient and an energy provider,

One might question how Acetyl L-Carnitine can sound more effective than L-Carnitine. Better known as the “modified version of L-Carnitine,” it is way simpler than L-Carnitine when it comes to comparing functions.

Let’s have a brief comparison between L-Carnitine and Acetyl L-Carnitine:


  • Act as an energy provider for mitochondria.
  • Ineffective at traversing the blood-brain barrier.
  • better for enhancing athletic performance due to its supplemental form.
  • L-Carnitine is absorbed into the bloodstream at a rate of less than 20%.

Acetyl L-Carnitine

  • It’s easier to absorb into the bloodstream directly.
  • ALCAR, or Acetyl L-Carnitine, not only provides an energy outlet for the mitochondria, but it also helps to maintain every single cell’s mitochondria by restoring its effective mitochondrial energy production level.
  • Significantly more effective at crossing the blood-brain barrier.
  • It also acts as an energy booster.
  • Acetyl L-carnitine is absorbed by the blood in 43 percent of cases. This is far more than L-Carnitine.

So, from the above brief comparison, we can conclude that why is Acetyl L-Carnitine considered the modified version of L-Carnitine?

What are the core benefits of consuming ALCAR?

After researching many clinical trials and studies, it was found that ALCAR has those abilities to suppress diseases like depression and has the potential to treat Parkinson’s disease.

ALCAR has the potential to meet the Mild Cognitive Impairment (MCI)

Mild Cognitive impairment is the stage of cognitive declination of a person that begins at a normal age and then develops into a serious problem of dementia.

While ALCAR has lots of memory aiding features that can reverse the stage of dementia, its daily consumption can increase the brain’s performance level.

Acetyl L-Carnitine has improved brain signaling.

While promoting better blood circulation, it is found that it helps in the faster growth of new neuritis that work as the working cable for our brain networking. Hence, by promoting the growth of neuritis, it helps in improving the signaling capacity of the brain.

Better for treating Chronic Fatigue Syndrome than

Their mental and physical fatigue improved after they were advised to take one gram of ALCAR daily.

Can ALCAR Treat Erectile Dysfunction?

If the patients are given two grams of acetyl-L carnitine, their libido increases, their sexual capacity improves, and they have an enlarged prostate within two weeks.

The Energy Optimizer for our brain cells

ALCAR knows the better utilization of glucose by injecting the non-oxidative activities that increase the acetylcholine level synthesized from the breakdown of glucose.

It acts as a fuel substrate for our brain and replenishes the energy levels consumed by the brain to reduce the amount of toxic by products.

A Guardian against the Oxidative Damage of Ecstasy (MDMA)

Due to the growing age factor, our brain cells are often damaged by oxidative stress and MDMA-induced neurotoxicity levels increase in our brain, clogging our potential cognitive thinking levels.

But when we start to take ALCAR, it provides strong neuroprotection over the damage and improves our memory and brain health by activating healthy brain enzymes.

How does Acetyl L-Carnitine work as a nootropic?

Acetyl L-Carnitine is known as the king of all Nootropic drugs due to its cholinergic efficiencies and better fuel substrate for the good functioning of our brain cells.

But how do we know that Acetyl L-Carnitine is a better option as a nootropic drug?

Rather than using the glucose energy breakdown, ALCAR focuses on increasing the cerebral glucose usage in metabolized form. Its highest nerve growth factor index makes it one of the most essential nootropics.

  • Increasing mental and physical strength.
  • acting as an anti-inflammatory agent by improving the percentage of glutathione.
  • So that our brain may function well, nutrient-rich blood circulation through every part of our brain is essential.
  • Better for the anti-aging supplement as it boosts cognitive abilities.

What are the side effects of Acetyl L-Carnitine?

However, if seen generally, Acetyl L-Carnitine is produced through a natural process within our bodies, but some people may have some allergic effects due to their body functioning, which is also very rare to be acknowledged.

Here are a number of side effects that can be reported:

  • Headaches
  • Psychosis
  • Higher blood pressure
  • lower blood sugar levels, etc.,

What are the precautions for Acetyl-L-Carnitine?

ALCAR should be avoided if a person has been reported to have certain sensitive issues within their bodies, such as:

  • Pregnancy in the case of a woman
  • Breastfeeding women
  • Bipolar disorder as it would lead to psychosis
  • Hypothyroidism

What is the recommended dosage of acetyl-L carnitine?

The expert recommendation for using Acetyl L-carnitine as a nootropic drug is to start with 500 mg of ALCAR on a daily basis, half in the morning and half after meals.

You can prepare a stack of ALCAR with other beneficiaries like:

Choline ALCAR + CDP

CDP choline is best used with ALCAR in a ratio of 1:4, i.e., 1 gram of ALCAR and 4 grams of CDP, as it is an initiator for promoting the Acetylcholine in our body.

ALCAR + Artichoke extract – booster for a higher brain energy synthesizing.

ALCAR + Ashwagandha – prevents the neurotransmitter breakdown and adding 300 mg of ALCAR with ashwagandha also gives you faster recovery from cognitive deficiency.

ALCAR + Bacopa Monnieri acts as an adaptogen and a mild acetylcholinesterase inhibitor.


ALCAR is without a doubt a wonderful nootropic agent that comes at a limited price and is really affordable. One can simply have an interaction with their doctor if they are on some other medication.

Because ALCAR improves our nerve growth factor along with glucose utilization and enhances our brain memory power, one must pay attention when adding it as a new supplement while enlisting the risks and precautions.

The anti-oxidation properties of ALCAR have lots of neuroprotective qualities that boost cerebral blood circulation and brain-derived neurotrophic factor.

ALCAR is really helpful for aging cognitive problems and helps stop Alzheimer’s disease, but again, a doctor’s consultation is a must!

Matthew Swayne

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